Dr. Heather Patisaul received her B.S. in Zoology in 1995 from the University of Florida and her Ph.D. from Emory University in 2001. Her lab and explores the mechanisms by which endocrine disrupting compounds (EDCs) alter neuroendocrine pathways in the brain related to sex specific physiology and behavior.
Dr. Patisaul is specifically interested in how estrogenic compounds, including phytoestrogens, impact the neural pathways which coordinate the physical and behavioral changes that occur across fetal development and during the pubertal transition. The lab uses a variety of traditional and transgenic rodent models (rats, mice and prairie voles) and employs a suite of neuroanatomical, neurobehavioral, and molecular testing strategies such as RNAseq, qtPCR, in situ hybridization, autoradiography and immunohistochemistry.
Dr. Patisaul is a NIEHS ONES Award recipient and has participated on several national and international expert panels and workshops related to health effects associated with soy and other endocrine disruptors including the 2010 World Health Organization Expert Panel on the health risks of Bisphenol A, and the 2012 Workshop on Low Dose Effects of Endocrine Active Chemicals co-organized by the US National Institute for Environmental Health Sciences/NIH and the Joint Research Center’s Institute for Health and Consumer Protection. She was also a member of the National Research Counsel Committee on Incorporating 21st Century Science Into Risk-Based Evaluations, and chair of the 2016 Gordon Conference on Environmental Endocrine Disruptors.
We welcome creative and motivated students to apply to join the lab, particularly undergraduates. Our work is interdisciplinary in nature and as such students can draw upon their experience and training in endocrinology, neuroscience, toxicology, and chemistry to build and execute independent projects within the overall theme of the lab. Collaborative projects among students in different departments are highly encouraged.
North Carolina State University is located in the Research Triangle Park region of North Carolina. This area is home to Duke University, University of North Carolina at Chapel Hill, the EPA, NIEHS, and numerous biotechnology companies. Opportunities for collaboration across institutions, both for research and training, are abundant.